PLOS Biology: Transferring a sick mother’s DNA to someone else’s egg ensures healthy children

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Transferring the cellular genome from an egg to the cytoplasm of a donor egg will enable women carrying the DNA mutations to give birth to healthy children. This was stated in a study by doctors from Peking University, published in the journal PLOS Biology.

Mitochondria, the powerhouses of the cell, contain their own DNA, mutations that can cause various inherited diseases. When a human conceives, the embryo inherits only the maternal mitochondria found in the egg.

To stop the inheritance of diseases, scientists have developed a method to insert parental DNA into the cytoplasm of donor cells bearing healthy mitochondria before fertilization. According to scientists, such a strategy is completely safe.

The authors of the study performed three different types of single cell analyzes from 23 post-transfer embryos and compared them with 23 IVF-derived control embryos.

The scientists found no genetic or functional differences between the resulting embryos and controls.

“We concluded that this method of fertilization is safe and does not inhibit embryonic development. However, given the limitations of the study, further measurements and larger evaluations are still needed to determine whether this method can be applied to a larger clinical trial group,” he said.

Formerly zoologists discovered There are remnants of DNA from animals that couldn’t be on Everest.

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