Glioblastoma is a rare brain tumor with extremely low survival rates. Its resistance to treatment is associated with special signals by which cancer cells “deceive” the immune system. This has been shown by a study published in the journal. Neuro-Oncology.
Immunotherapy is a cancer treatment method that relies on the ability of immune cells to recognize and destroy tumors. It has made it possible to treat many types of tumors that previously had no chance of survival. However, in the case of glioblastoma, immunotherapy was ineffective.
Typically, the resistance of cancer cells to treatment is associated with the development of mutations. However, this is a long process that requires changes to the cell’s DNA. In a new study, scientists found that glioblastoma cells change their appearance, making them look like normal cells. Therefore, the immune system does not attack them and immunotherapy becomes ineffective.
Biologists have also found specific molecules involved in this hoax. They could form the basis of new types of immunotherapy to fight glioblastoma.
Previously, scientists for the first time Experienced HIV drugs to treat brain tumors.