Specialists in “Eye Microsurgery” named after academician SN from Sechenov University and MNTK. Using X-ray microtomography, Fedorov learned to identify markers to predict the growth and metastasis of a malignant eye tumor (uveal melanoma). This issue was told to socialbites.ca at the First Moscow State Medical University named after him. Sechenov.
“Uveal melanoma is a rare but extremely aggressive tumor that develops from the pigment cells in the choroid of the eye. Distant metastases affecting the liver develop in half of the patients, 90% of them. Despite the possibilities of modern surgical treatment, radiation and laser therapy, metastatic tumors occur, which explains such a high mortality rate in uveal melanoma. “Unfortunately, there are currently no effective methods of chemotherapy or immunotherapy for primary or metastatic foci of uveal melanoma because our knowledge of the mechanisms of metastasis is limited, making this study particularly relevant.” A young researcher from the Regenerative Institute. Medicine told socialbites.ca Sergei Tkachev.
The risk of developing metastases and, accordingly, the prognosis of the disease is associated with certain features of uveal melanoma. Researchers will analyze relationships between patient data and patterns of tumor growth and metastasis. This will allow us to collect a patient database containing the results of all laboratory and instrumental studies.
The main research method of the project is X-ray microtomography. This advanced technology allows 3D imaging of tissue with light microscope-level resolution while preserving its natural architecture. Combining this approach with molecular genetic research and digital pathology methods, the scientists plan to identify patterns in exactly how tumor cells interact with human eye tissue.
The results of the project will help formulate new criteria for more accurate diagnosis, staging and prognosis of the course of the disease. In addition, the approach developed by scientists will form the basis for studies on any tumor tissue.
It was before was created A method for assessing hemoglobin in blood using light.