Specialists of the Department of Human Anatomy and Histology of the First Moscow State Medical University named after him. TO THEM. Sechenov from the Russian Ministry of Health proposed for the first time in Russia the use of heat shock proteins (produced in the body when the temperature rises) weighing 70 kilodaltons to combat neurodegeneration. socialbites.ca was told about this at Sechenov University.
The incidence of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis is increasing. Today, it is not possible to treat all these diseases. If they continue for a long time, they significantly reduce the patient’s quality of life: Memory loss, impaired coordination and motor activity are factors that can lead a person to disability.
One of the most promising areas for treatment is the use of heat shock proteins weighing 70 kilodaltons.
“In our laboratory, we have transgenic mouse lines that actively produce heat shock proteins. We cross them with two other lines that develop conditions that model the development of amyotrophic lateral sclerosis and Alzheimer’s disease,” Gennady Pyavchenko, associate professor at the department of human anatomy and histology at Sechenov University, told socialbites.ca. their offspring will carry both genes: increased production of heat shock proteins and Alzheimer’s disease or amyotrophic lateral sclerosis.
Scientists suggest that by steadily increasing the production of heat shock proteins, the development of neurodegenerative diseases will either slow down or almost completely disappear.
The mice have now begun producing offspring, and scientists will begin to directly examine the effects of heat shock proteins on slowing the development of neurodegeneration.
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