Scientists from Texas A&M University have found that unhealthy diets can lead to diabetes and the buildup of toxic proteins in the brain, leading to the cognitive impairment characteristic of Alzheimer’s disease. In this respect reports American Society for Biochemistry and Molecular Biology (ASBMB).
In experiments on laboratory mice, scientists found that a high-fat diet suppressed the expression of a protein called Jak3. In rodents with decreased Jak3 synthesis, a cascade of inflammation was observed throughout the body, starting from the intestines and progressing to the brain.
Scientists explained that malnutrition often leads to low-grade chronic inflammation and subsequent diabetes. But inflammation in the brain can also reduce the organ’s ability to get rid of toxic proteins. These include amyloid and Tau proteins. Their accumulation in brain tissue causes neuronal dysfunction, manifesting as attention and memory disorders.
Researchers also noted that a healthy diet reduces the likelihood of triggering inflammation in the body, thus preventing Alzheimer’s disease and diabetes. Another important factor in reducing risks is controlling your blood sugar levels.
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