Scientists have found a substance in female ginseng that prevents the formation of cells that destroy bone tissue in osteoporosis. The results were published in the journal ACS Center for Science.
Scientists discovered two new compounds (falcarinphthalides A and B) in an extract of female ginseng or Chinese angelica (Angelica sinensis). They were able to synthesize this substance in quantities sufficient for biological testing in the laboratory.
Experiments on cells showed that falcarinphthalide A and its precursors suppressed the activity of osteoclasts, cells that play a central role in bone resorption. The substance blocked important molecular pathways for osteoclast formation.
The study opens up the possibility of new osteoporosis drugs based on a compound derived from female ginseng. This disease is accompanied by bone loss and can lead to hip and spine fractures.
According to the International Osteoporosis Foundation, low bone mass affects 54 million American adults over the age of 50. Various medications have proven effective in preventing bone loss or promoting bone formation. But all have potential side effects, including damage to jaw bones and legs.
Previous scientists I learnedIt says that quitting smoking and being physically active reduces the risk of hip fracture by 45%.