A high-fiber diet may delay the onset of symptoms of Huntington’s disease. This has been shown by a study published in the journal. Brain, Behavior and Immunity.
Huntington’s disease is an inherited, progressive, neurodegenerative disease that is always fatal. Patients complain of worsening motor, cognitive and psychiatric symptoms over many years. The disease also causes gastrointestinal symptoms. Recent studies have shown that this changes the species composition of gut bacteria.
In the new study, researchers compared the effects of high, moderate, and no fiber intake on a mouse model of Huntington’s disease. The more fiber an animal has in its diet, the better their gastrointestinal systems function and the more normal their mental functions and behavior. Scientists attribute this effect to fiber’s effect on the microbiome-gut-brain axis.
But the gut microbes of healthy mice responded differently to the fiber. This highlights that the gut microbiome is different in Huntington’s disease. Scientists have already begun working on clinical trials of the diet in humans.
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