Researchers from Sao Paulo State University (UNESP) in Brazil spent Experiments on mice have helped understand why children of women who are malnourished during pregnancy face a higher risk of prostate cancer as adults. The study identified changes in gene expression that may be associated with hormonal imbalance and increased risk of prostate cancer.
Another study found an association between a protein-restricted diet during pregnancy and lactation in rats and an increased risk of prostate cancer in their offspring. In both cases, research suggests that nutrition and environment early in development can determine the course of health and disease in offspring.
A study using bioinformatics found that prostate cancer in juvenile and aged rats may be caused by the release of miR-206 and its target gene PLG in early life. This liberalization was likely caused by abnormally high estrogen levels during pregnancy. Changes in the gene expression profile may persist throughout the life of rats and predispose them to prostate cancer as they age. One of the altered genes, ABCG1, was a potential “DOHaD gene” associated with abnormal prostate development, which has long-term consequences and can increase the risk of cancer.
The study was supported by the Sao Paulo Research Foundation (FAPESP).
Previously, most men no need to check Fingered prostate to exclude cancer.
used to be a doctor named Risk factors for prostate cancer.