Multiple myeloma treated after hepatitis treatment indicates that this tumor may be caused by hepatitis viruses. The discovery was published in the journal hematological.
Multiple myeloma, a specific type of malignant tumor, produces large numbers of abnormal cells that produce antibodies that protect against a particular infection. A few years ago, a patient in Spain was cured of multiple myeloma after doctors treated him with an antiviral drug for hepatitis C. As a result, the excessive proliferation of cells producing antibodies against hepatitis C in the bone marrow stopped.
To find out whether treatment of myeloma was associated with antiviral therapy, researchers conducted a study of 54 patients with hepatitis B or C. All of the participants also had monoclonal gammopathy, a condition that often precedes multiple myeloma. Scientists confirmed that patients had excessive amounts of antibodies targeting the hepatitis virus in their bodies.
The researchers then moved on to examining 1,300 multiple myeloma patients infected with hepatitis B and 1,200 multiple myeloma patients infected with hepatitis C. In both cases, those who received antiviral treatment were significantly more likely to survive.
Scientists believe that patients with hepatitis B or C should start antiviral treatment as early as possible. It is also important to exclude these infections in people with monoclonal gammopathy to prevent the development of malignancy.
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