New research shows that people who live to be 100 or more often have low levels of glucose, uric acid and creatinine in their blood. The study was published in the journal geroscience.
The scientists used data from 44,636 people who had blood tests done at the Central Automation Laboratory in Stockholm between 1985 and 1996. 1,224 people lived to be one hundred years old. Blood counts were monitored until the end of 2020. Researchers analyzed 12 biomarkers: uric acid to assess inflammation, total cholesterol and glucose to assess metabolic health, ALT and AST enzymes, albumin, gamma-glutamyltransferase, alkaline phosphatase and lactate dehydrogenase to assess liver function, creatinine, iron to assess kidney health. and ferritin. to rule out anemia.
Centenarians had lower (but not exceptionally low) levels of glucose, uric acid, and creatinine in their blood than people who did not live to be a centenarian. In general, centenarians were less likely than others to have blood biomarker levels at the extremes of the normal range. These differences in blood biomarkers were observed as early as age 65.
All blood parameters examined depend on lifestyle, so they can be affected. For example, high levels of uric acid are typical of people who abuse alcohol and meat. Any type of activity, including daily activities that are not related to exercise, can help reduce glucose and creatinine levels.
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