Scientists from Karolinska Institute found that increased metabolism in mitochondria may signal Alzheimer’s disease. results published In the journal Nature.
Alzheimer’s disease is the most common form of dementia. The disease is characterized by a decrease in mental abilities, speed of thinking, reaction and spatial orientation skills.
Researchers have found that an early sign of Alzheimer’s disease may be an increase in mitochondrial metabolism. Mitochondria are organelles that participate in cellular respiration and provide energy to the cell. It turned out that the increase in metabolic rate in the mice’s mitochondria was followed by changes characterized by the disruption of synapses (the places of contact between two neurons or between a neuron and a cell receiving signals). Researchers suggest that such a biomarker could signal the onset of Alzheimer’s disease in humans.
Scientists stated that Alzheimer’s disease begins to develop 20 years before symptoms appear. Researchers hope that monitoring metabolic changes in mitochondria will become widespread as a method for early diagnosis of this disease. This will allow patients to start treatment on time.
used to be a doctor named unclear cause of dementia.