Scientists from Wuhan University of Science and Technology proposed using dental pulp stem cells and products to repair peripheral nerves. The study was published on: World Stem Cell Journal.
Peripheral nerve damage seriously affects people’s quality of life. Stem cell therapy is considered a promising new treatment option for this condition.
As the authors of the new study show, dental stem cells, particularly pulp stem cells (DPSCs), have significant potential in the field of neural tissue engineering. Pulp is a special connective tissue that fills the tooth cavity. It is full of blood vessels and nerves. Stem cells are easy to isolate, can give rise to a wide variety of new cell types, and also cause almost no immune response and therefore survive better. Additionally, pulp stem cells are suitable for long-term storage.
In a recent groundbreaking study, DPSC transplantation treated neuropathy in diabetic rats. The procedure resulted in restoration of nerve function.
Pulp stem cells have already proven useful in tissue engineering and regenerative medicine, including the treatment of sciatic nerve, facial nerve, spinal cord and other neurodegenerative diseases. These cells may also be useful in the treatment of osteoarthritis due to their ability to turn into cartilage tissue. Scientists hope that these stem cell applications will soon be approved for treatment in humans.
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