Novosibirsk State University has developed a method to estimate the risk of reproductive disorders in women with subclinical and overt hypothyroidism. socialbites.ca was told about this at NSU.
Hypothyroidism is a disease of the endocrine system characterized by a deficiency of thyroid hormones. These hormones regulate metabolism, affect the emotional background and the body’s resistance to stress and stress. Deficiency of thyroid hormones can lead to serious health problems: it can disrupt the functioning of the heart and kidneys, cause obesity, reduce immunity and lead to infertility. In women, this disease is detected 5-10 times more often, and sometimes the diagnosis of hypothyroidism is made late; in 10% of cases, hypothyroidism is not detected at all.
“Women seek medical help due to infertility or disorders in the functioning of the reproductive organs, and one of the reasons may be hypothyroidism, because hypothyroidism contributes to hormonal imbalance in the body,” said the study’s author, an associate professor at the department of medicine. Obstetrics and gynecology at Novosibirsk State University Evgenia Kudinova.
Using venous blood analysis, scientists learned to diagnose creatine phosphokinase (CPK) (an enzyme associated with indicators of the state of the reproductive system) and blood homocysteine markers. (Oxidation in plasma is accompanied by the accumulation of free oxygen-containing radicals that damage the vascular endothelium). As it turned out, an increase in the level of CPK and homocysteine is often accompanied by reproductive complications in hypothyroidism
“Thus, we confirmed that the level of the markers examined in the blood can serve to predict the risk of developing disorders in the reproductive function of the body in women with hypothyroidism. Kudinova noted that timely detection of increased CPK and homocysteine is very important for the effectiveness of the applied treatment strategy.
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