Researchers at Privolzhsky Research Medical University (PIMU) have developed the “DS-ELISA-ANTI-BLV” test system, which for the first time implements the “sandwich” format of enzyme-linked immunosorbent testing and allows the detection of two substances. antibodies against leukemia virus proteins instead of a. socialbites.ca was told about this by the press service of Sociocenter, the operator of the Priority 2030 program.
This significantly increases the effectiveness of serological diagnosis of leukemia, ensuring the detection of infection at an early stage and high reliability of the analysis results. The system has been successfully tested and is currently used in veterinary laboratories.
“The leukemia virus primarily affects the immune system, and animals infected with it become more susceptible to other (both infectious and non-infectious) pathologies. The disease caused by this virus cannot be cured, reduces the productivity of animals and deteriorates the quality of milk. The asymptomatic stage can last for several years and the animal spreads the infection. Therefore, in the system of implementation of sanitary measures against leukemia in cattle, diagnosis has the most important place,” Elena Dabakhova, head of the Center for Agrobiotechnology of PIMU, explained to socialbites.ca.
In other diagnostic tools on the Russian market, the targets are antibodies that recognize only the gp51 antigen. When such testing systems are used in the early stages of infection, the probability of false results is high, so a confirmatory test is required, increasing the cost of diagnosis.
In accordance with current standards, all cattle are examined for leukemia at least once a year (twice a year for breeding animals). Inspection is also carried out when buying, selling, transporting live animals or when signs of disease appear. With the diagnostic test system “DS-ELISA-ANTI-BLV” the risk of error is significantly reduced.
Currently, the system is used in veterinary laboratories in Belgorod, Kemerovo, Leningrad, Lipetsk, Penza, Saratov regions, the Republic of Bashkortostan, Kalmykia, Komi, Tatarstan and many other regions that are part of the State Veterinary Service of the Russian Federation. Regions of Russia.
Previous scientists was created Virus-resistant calf using genetic engineering.