Scientists from the University of Maryland School of Medicine in the USA have discovered a link between brain inflammation and the risk of developing schizophrenia and autism in children. The results of the study were as follows: published In Science magazine.
Encephalitis is a pathological process that affects the brain substance. Infectious forms of the disease occur due to the penetration of pathogenic microorganisms (bacteria, viruses, fungi). Inflammation can also develop on the background of autoimmune diseases, taking pharmaceutical drugs or after vaccination.
The study found that inflammation in early childhood prevents some neurons in the cerebellum from fully maturing. The cerebellum is the brain region responsible for motor control and cognitive functions used in speech, communication and emotional regulation. Two types of cerebellar neurons were most vulnerable to brain inflammation: Golgi and Purkinje neurons.
During development, Purkinje neurons form synapses that connect the cerebellum to other brain regions involved in cognition or emotional control. Golgi neurons coordinate communication between cells within the cerebellum. Disruption of any of these processes can potentially lead to autism spectrum disorders and schizophrenia in children.
Scientists added that this discovery may contribute to the development of new techniques that will increase the effectiveness of treatment of neurological disorders.
Previously neurologist listed autism treatment methods.