A group of scientists from SPbPU (St. Petersburg Polytechnic University Peter the Great) has discovered a new way to combat Alzheimer’s disease. It turns out that cognitive function can be restored if astrocytes, the cells that regulate neuronal activity, are affected in a specific way. Research results published In International Journal of Molecular Sciences (IJMS).
Alzheimer’s disease is the most common form of dementia. This disease affects the brain and makes it difficult to think, impairing memory and other cognitive functions (speaking, writing, and spatial orientation). Alzheimer’s disease is caused by damage to the synapses through which signals are transmitted from one neuron to another.
Scientists from St. Petersburg Polytechnic University suggested that it is possible to normalize the functioning of neurons by stimulating astrocytes. These are cells that provide nutrients to neurons, as well as surrounding synapses and regulating their activity. Scientists conducted an experiment on laboratory mice; They shed light on a sensitive protein located outside the membrane of these cells. The light caused astrocytes to release gliotransmitters, molecules that restore neuronal plasticity and speed up the transmission of nerve impulses.
Researchers suggest that gliotransmitters may rebuild connections between neurons damaged during the development of Alzheimer’s disease.
It was before named A product that helps fight Alzheimer’s disease.