Scientists from the Zanjan University of Medical Sciences found that the DASH diet led to a decrease in the level of uric acid in the blood serum. Previously, an increase in its concentration was associated with cardiovascular diseases, and the deposition of uric acid crystals in the joints leads to the development of gout. Research published in the journal scientific reports.
Researchers searched the PubMed, Web of Science, Scopus, and Embase databases for publications. They focused on randomized controlled trials (RCTs), which are the highest quality medical trials. In these, the keto and DASH diets were followed by adults for at least two weeks.
Initially, the scientists found 26,915 publications. After eliminating irrelevant and repetitive ones, they included ten RCTs in the final analysis, including four and six examining DASH and ketogenic diets, respectively.
Evaluation of clinical trials of the DASH diet involving 590 people showed that after at least 28 days of dieting, the blood uric acid level of the participants was significantly reduced.
267 people participated in studies on the ketogenic diet. The ketogenic diet had no effect on uric acid levels.
The DASH (Dietary Approaches to Stop Hypertension) diet was developed for people with high blood pressure. Her diet is rich in fruits, vegetables, whole grains and low-fat dairy products, limits the addition of salt, saturated fats (found in palm and coconut oils, pork, beef, and full-fat dairy products) and sugar.
The ketogenic diet was originally developed for use in children with epilepsy. This low-carb, high-fat, moderate-protein diet causes the liver to produce more ketone bodies. The ketogenic diet is being actively studied, but so far its benefits have been conclusively proven only for children.
The researchers concluded that the inclusion of the DASH diet in patient regimens may be beneficial for high uric acid levels. DASH needs to be compared with other dietary approaches, including Mediterranean and vegetarian diets, to determine which diet is best for lowering serum uric acid levels.
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