Scientists at Ben-Gurion University in the Negev have found that adding the naturally occurring substance bisindole to toothpastes and mouthwashes can help prevent plaque and cavities. Research published in the journal antibiotics.
In laboratory experiments on microbes, scientists found that 3,3′-diindolylmethane (DIM), a naturally occurring molecule also known as bisindole, reduced bacterial biofilms by 90%. S. mutants. This microorganism is found in the mouth of all healthy people and as it grows it covers the teeth with a biofilm associated with plaque formation, caries and enamel destruction.
Destroying the biofilm stopped the growth of bacteria. Bisindol has also been found to have anti-cancer properties. The molecule, which has been found to have low toxicity, can be added to toothpastes and mouthwashes.
The study was led by scientists from Ben-Gurion University in the Negev and colleagues from the University of Sichuan and the National University of Singapore.
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