Scientists from Harvard Medical School found that people with the second blood type have an increased risk of SARS-CoV-2 infection. Research published in the journal Blood.
The researchers conducted laboratory experiments on blood cells obtained from people with blood types A(II) and O(I). They found that the SARS-CoV-2 virus predominantly infects cells of the second blood group.
The result was due to the fact that the virus has a greater affinity for proteins on the surface of cells with the second blood group – this makes it easier to penetrate cells. The scientists also showed that adding a protein that prevents the virus from recognizing proteins on the surface of cells prevents infection of blood group II cells.
Previous studies have shown that people with blood type II may be up to 20% more likely to become infected after exposure to SARS-CoV-2 than people with blood type One. However, no study has yet identified a mechanism that could explain this difference.
The scientists cautioned that the findings do not mean that people with blood type O do not need to take precautions to reduce their risk of contracting SARS-CoV-2.
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