Scientists at Florida Atlantic University have found that running in midlife helps the brain maintain connections between nerve cells, which can prevent or delay memory loss with aging. The research was published in the journal eNeuro.
It has previously been shown that new neurons (nerve cells) can form in the brains of animals, including humans. But it was unclear how well they integrate into existing neural networks and whether this would be affected by physical activity.
To answer these questions, the researchers used a unique approach to monitor neural circuits in rodents using a modified rabies virus. The results showed that new neurons formed during the animals’ early adulthood are integrated into a network of neurons associated with the maintenance of episodic memory during aging. Mice that ran regularly had significantly more new neurons and connections in the brain.
“Our study provides insight into how regular exercise, beginning at a young age and continuing through middle age, helps preserve memory function during aging and highlights the importance of incorporating exercise into our daily lives,” the scientists said.