Scientists from the Don State Technical University (DSTU), together with colleagues from the Rostov, Bashkir and South Ural Medical Universities, proposed the use of hydrogen sulfide to protect cells in various pathological conditions. This was reported to socialbites.ca in the press service of the Priority 2030 program of the Ministry of Science and Higher Education of the Russian Federation.
Hydrogen sulfide best protects the cells of the body compared to other gas conductors (molecules – gas conductors). These include nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H2S), and sulfur dioxide (SO2). Hydrogen sulfide, produced in the human body, can act as an antioxidant, increase the level of enzymes of the antioxidant defense system, reduce inflammation, oxidative stress, neuroinflammation, as well as apoptosis (cell death process).
The level of a particular gaseous donor in the human body can vary. At the same time, the gas transmitters themselves can have different effects on the cell – cytoprotective (cell protection) or cytotoxic (cell damage). The imbalance of these molecules can lead to the development of serious pathologies.
“With a traumatic brain injury, the level of hydrogen sulfide in the human brain usually decreases. The main enzymes responsible for hydrogen sulfide synthesis in the human body are cystathionine beta synthase and cystathionine gamma lyase. The regulation of these biocatalysts can form the basis for the development of effective neuroprotective drugs. However, excess H2S’ It is worth noting that slag can lead to negative effects, especially increased oxidative stress, ”Stanislav Rodkin, senior lecturer at the Department of Bioengineering at DSTU, told socialbites.ca.
As a result of their research, scientists concluded that the drugs that will include gasifiers will have a beneficial effect on the human body in various diseases.