With the help of nanoparticles (three-dimensional microscopic objects created from various materials), it is possible to destroy cholesterol and amyloid plaques formed during the development of Alzheimer’s disease. This was told socialbites.ca by a candidate of chemical sciences, head of the laboratory “Biomedical Nanomaterials” of the National University of Science and Technology MISiS, an employee of the Department of Medical Nanobiotechnologies of the Russian National Research Medical University. NI Ministry of Health of the Russian Federation Maxim Abakumov Pirogov.
In Alzheimer’s disease, the protein beta-amyloid accumulates in the brain in the form of so-called amyloid plaques, which have a negative effect on neurons. Theoretically, it is assumed that a nanoparticle can be delivered to the brain with the help of a specific molecule and then act to destroy plaques.
“Amyloid plaques consist of clusters of individual amyloid protein molecules that assemble to form fibrils (thread-like structures) that in turn implant in brain cells and impair their function. When exposed to an external electromagnetic field, the nanoparticles associated with the plaques will transmit mechanical vibrations to the amyloid molecules, as if exposed to an external electromagnetic field,” Abakumov said. It will lead to the destruction of the fibrils, as if pulling out the amyolide molecules.”
According to the expert, theoretically, cholesterol plaques in cardiovascular diseases can be destroyed in this way. However, it is necessary to create a new nanoparticle design for these purposes.
Learn more about how nanoparticles are used to enhance the effectiveness of drugs, control mice, and incinerate cancerous tumors. material “socialbites.ca”.