NUST MISIS experts together with colleagues from the AI University of Chemistry and Technology. DI. Mendeleev is working on a way to improve the effectiveness of drugs using nanoparticles, this was told socialbites.ca by a candidate of chemical sciences, the head of the laboratory “Biomedical Nanomaterials” of NUST MISiS, employee of the Department of Medical Nanobiotechnologies. Russian National Research Medical University. NI Ministry of Health of the Russian Federation Maxim Abakumov Pirogov.
“We investigated the possibility of combination in the administration of two drugs. There is such a phenomenon: when two drugs do not work very effectively on their own, but when in a given combination they increase their effect significantly. And sometimes. But the problem is that they are in one place where they act at a strictly defined rate. For example, 1 to 10 drugs A to B give a great result, and take 1 for 1, then they work even worse than separately, ”explained the biochemist.
Because the drugs are different, scientists cannot administer them to a person simultaneously and intravenously. However, you can cheat them and place them in a nanoparticle, Abakumov said, – then they will already be distributed in the cells at the same rate.
“So far we have had good results in experiments on cell cultures, and we plan to conduct a series of experiments on living organisms,” said the expert.
Learn more about how nanoparticles are used to control mice, incinerate cancerous tumors, and predict the effectiveness of anti-cancer treatments. material “socialbites.ca”.