Scientists have created a device that is implanted directly into the body for the treatment of pancreatic cancer. An article about this was published in the journal Advanced Science.
Immunotherapy is one of the most effective ways to treat cancer, where the effect is achieved by stimulating one’s own immune system. The immediate application of this method to the whole body has a significant disadvantage, which causes many side effects.
Now Corrin Ying Xuan Chua and colleagues have created an implant with a drug injected directly into the pancreas to treat adenocarcinoma. Adenocarcinoma of the pancreatic ducts is often diagnosed at an advanced stage. In fact, approximately 85% of patients already have metastatic disease at the time of diagnosis and therefore require very vigorous treatment.
A metal container about the size of a grain of rice contains liquid containing anti-CD40 monoclonal antibodies (mAbs) considered promising immunotherapeutic agents. During experiments on mice, it was revealed that the implant reduced the tumor at a dose of the active substance four times lower than conventional immunotherapy. In addition, not only the tumor in which the implant was placed, but also the adjacent tumor shrank.
The authors hope their device will make it easier and more effective to treat cancer.
ancient biologists raised artificial fat for “tube meat”.