Moscow State University Lomonosov named after MV will receive more than 126 million rubles for the production of a fertility drug, which has shown its effectiveness in clinical trials and animal experiments. This was reported by the press service of the university.
Scientists explained that human mesenchymal stromal cells, with the help of special substances, can stimulate the restoration of the structure and functions of damaged tissues, including humans. The new drug was created on the basis of substances secreted by these cells.
“The drug is a mystery, that is, it is a complex of purified biologically active factors, such as proteins, lipids, regulatory RNAs, produced by human mesenchymal stromal cells into the extracellular environment,” said the head of the laboratory for tissue repair and regeneration. Institute of Regenerative Medicine, Moscow Research and Educational Center, MSU, Ph.D. Anastasia Efimenko.
The use of the secretome was comparable in efficiency to the action of the cells themselves, but it turned out to be safer. The drug restored the fertility of male mice and they were able to produce healthy offspring.
Scientists expect their development to improve the treatment of male infertility unresponsive to other methods. Clinical trials will be held at the Moscow Research and Education Center named after MV. Lomonosov. It is also planned to equip the research and production site on the basis of the International Research and Training Center, where the first batches of a new drug for clinical trials will be obtained.