Chronic sleep deprivation greatly reduces the effectiveness of hepatitis and flu vaccines. In this respect informs TASS citing the University of Chicago.
The COVID-19 pandemic has forced doctors to discover what factors may affect the effectiveness of vaccines. That is, it can be reduced by lifestyle features: RNA vaccines are less effective when administered to the body of smokers and obese people.
Karina Spiegel and her colleagues decided to find out how sleep quality affects the immune system. To do this, they analyzed nearly 20 previous studies on vaccination against hepatitis and flu. In particular, it turned out that chronic lack of sleep, less than six hours of sleep per night, similarly reduced the average concentration of antibodies in the body of vaccinated volunteers when using all flu and hepatitis vaccines studied.
As a result, the average lifespan of vaccine-derived antibodies was shortened by about two months, negatively impacting the level of protection afforded by flu and hepatitis vaccines. According to the researchers, this was typical for men, where the lack of sleep was about twice as strong. The reason for the gender differences in the effect of sleep on antibodies is not yet clear to experts.
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