MIPT biophysicists develop a new way to treat arrhythmia

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A method for the treatment of arrhythmia was developed by biophysicists from the Experimental and Cellular Medicine Laboratory of the Moscow Institute of Physics and Technology by implanting stem cells delivered to the affected areas of the heart on microcarriers. This was reported to socialbites.ca at the Ministry of Education and Science.

One of the causes of arrhythmia is the wounds and wounds on the heart that occur after a heart attack or ischemia and disrupt the passage of electrical impulses from the heart. Currently, the only way to treat such an arrhythmia is radiofrequency catheter ablation, that is, “burning” the focus of the arrhythmia using high-frequency electric current. Scientists decided to create a method that would allow to repair damaged tissue without surgery.

“We decided to create a microcarrier that could be introduced into the body in a minimally invasive way. They took a separate fiber with a specific composition and “planted” a stem cell on it. It is important that the cell is also at a certain stage of its development and transformation into a cardiomyocyte. After we sent a microcarrier, we began to wait for it to take root.

It turned out that when injections with microcarriers were used, the survival of cell cultures was much higher than when polymers that formed “patches” on heart tissue were used, or when a cell suspension was given directly to replace damaged tissue. The team is now testing the effectiveness of the new technology in all organs and animals.

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