A group of French scientists from the university hospital Bordeaux discovered that body weights known as “Yo-Yo Diet” significantly increased the risk of kidney disease in patients with type 1 diabetes. The study was published scientifically broadcasting Journal of Clinical Endocrinology and Metabolism (JCEM).
The Yo-Yo diet, characterized by multiple reduction and weight gain, is common between 35% of men and 55% of women. The name of this diet is associated with a yo-yo toy (designs from two discs connected to an axis) that falls along the rope connected to the axis under the influence of the inertia.
Previously, such a nutritional model was proven to increase the risk of cardiovascular disease both in the population and in people with type 2 diabetes.
Researchers analyzed the data of 1432 participants in the “DCCT) and the epidemiology of intervention and diabetes complications” (EDIC). For each person, they examined the six -year body weight indicator by using the “average variability index (VIM) index, which measures higher weight fluctuations than average value.
The results showed that the initial values of the participants with more significant weight fluctuations decreased 40% of the initial values of glomerular filtration (SCF). SKF is an indicator of how well the toxins of the kidneys filter from blood. In addition, albinuria has been detected more frequently in such patients – an increasing amount of albumin protein, which is a symptom of kidney disease in urine.
Although the mechanisms that damage weight fluctuations damage the kidneys were not fully examined, the authors of the study proposed several hypotheses. One of the possible reasons is insulin therapy for Type 1 diabetes treatment that can contribute to the cycle of weight. In addition, frequent changes in body weight constitute an additional load that can aggravate the damage given to the kidneys on the heart and blood vessels.
Previously, scientists learnedIn this case, obesity does not reduce a person’s life expectancy.
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Source: Gazeta

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