Scientists from the University of Bath (UK) have suggested that psoriasis may be caused by a malfunction in the hormone responsible for regulating iron levels. Research results It was published In the journal Nature Communications (NatCom).
Psoriasis is a chronic autoimmune disease that primarily affects the skin. Typically, psoriasis manifests itself as inflammation and the formation of red, dry, raised patches on the surface of the skin. Although scientists cannot say for sure what causes flares, it is believed that in people with psoriasis, the skin produces too many cells and these cells build up, causing itchy rashes.
According to British scientists, the cause of psoriasis may be a malfunction of the hormone responsible for regulating iron levels. Researchers explained that iron is essential for transporting oxygen throughout the body’s circulatory system and maintaining healthy skin. However, when the skin produces too much iron, this ingredient can increase exposure to ultraviolet radiation and cause excessive skin cell growth.
Experiments on mice revealed that the “blame” for excess iron production lies with the hormone hepcidin, which controls how much iron from food is absorbed and released into the body. In healthy people, the hormone is produced only in the liver, but in psoriasis patients it is also found in the skin.
Researchers have suggested that regulating hepcidin levels may provide relief for people with psoriasis. More research is needed to develop new, effective treatment strategies for this disease.
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Source: Gazeta
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