Scientists link low manganese levels to intestinal inflammation 09.15.2024, 23:26

Low manganese levels may worsen inflammatory bowel disease, as shown in a study published in the journal Neurology. Nature Communication.

The SLC39A8 gene is responsible for the production of a protein that transports manganese and zinc. In a new study, scientists found that mutations in the SLC39A8 gene are associated with an increased risk of manganese deficiency. These mutations are common in people with inflammatory bowel diseases, such as Crohn’s disease and colitis. The discovered association supports the hypothesis that manganese deficiency increases the risk of inflammatory bowel disease.

Manganese is essential for the functioning of many body systems, including immunity, bone formation, and carbohydrate metabolism. This mineral is found in plant foods: whole grains, beans, rice, nuts, and vegetables. A modern diet rich in animal products can lead to manganese deficiency. The authors of the study note that manganese consumption in developed countries has decreased by more than 40% in the past 15 years. This may lead to the spread of inflammatory bowel disease.

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Source: Gazeta

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