Scientists from Osaka Metropolitan University (Japan) found that cancer treatment in obese people sometimes reduces the risk of death. Results It was published In JAMA Network Open.
Scientists analyzed data from more than 500,000 Japanese lung cancer patients to understand how body mass index (BMI) was related to mortality in immunotherapy and traditional chemotherapy.
The research team focused on patients with advanced non-small cell lung cancer. They found that the higher the BMI (the higher the person’s body weight), the lower the risk of death with both types of treatment. But the situation changed for people with a BMI over 24.
Scientists also found that patients with a BMI below 28 had a lower risk of early death with immunotherapy than with chemotherapy. Those with a BMI of 28 or greater had an increased risk of death during immunotherapy and a decreased risk of death during chemotherapy.
Scientists have suggested that immunotherapy is not always the best treatment option for people with advanced non-small cell lung cancer. A range of factors, including age, hormonal levels and gut microbiota, are likely to affect the effectiveness of treatment.
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Source: Gazeta
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