A new culprit of Parkinson’s disease was found 18:01

Scientists have discovered the mechanism of a molecular switch that protects the brain from the development of Parkinson’s disease. The results of the research were published in the journal Science Developments.

In previous studies, the authors showed that the PINK1 gene plays a central role in protecting brain cells from stress. Patients with a mutation in this gene lose the cells that control movement and develop symptoms of Parkinson’s disease.

PINK1 is responsible for the production of a special molecule that signals damage to mitochondria, the energy stations of cells. When this happens, PINK1 activates the damage repair process. However, the activation mechanism was previously unknown.

In a new study, scientists found that activation of the PINK1 switch requires a complex molecular machine on the surface of mitochondria known as the translocase outer membrane (TOM). The molecules involved in its formation may become the target of new drugs against Parkinson’s disease.

Parkinson’s disease causes serious movement disorders. No drug has been developed that can slow or stop the progression of the disease.

Previously a feature of the salivary glands connected With symptoms of Parkinson’s disease.

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Source: Gazeta


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