Neurologists from Lund University in Sweden discovered that the age at which dementia develops can be affected by the formation of brain folds in the womb. They talked about it in a magazine article. cerebral cortex.
Frontotemporal dementia, as the name suggests, is a neurodegenerative disease that affects the frontal and temporal lobes of the brain. This leads to a loss of empathy, inappropriate behavior, carelessness, and loss of one’s ability to plan one’s actions. Compared to other forms of dementia, frontotemporal dementia occurs earlier, usually before age 60. Life expectancy after diagnosis is 8-10 years.
The researchers compared the brain MRI results of 307 volunteers aged 27 to 87, of whom 92 had Alzheimer’s disease and 105 had frontotemporal dementia. It turns out that the folds formed at the stage of fetal development affect the age at which the symptoms of frontotemporal dementia appear. They were not associated with Alzheimer’s disease.
“The specific area we studied is called the cingulate gyrus, located in the frontal lobe of the brain. Study participants who had an extra crease in this area in the right hemisphere of the brain developed symptoms of frontotemporal dementia an average of 3 years after people without this wrinkle,” he said.
Scientists think the new data will be useful in assessing the risks of developing dementia and early detection. Exactly how the described features of the brain affect the development of dementia and whether this effect can be compensated remains to be seen.