The founder and head of 343 Industries Bonnie Ross (Bonnie Ross) announced her departure from the studio and Microsoft. According to Ross, she is dealing with health problems in the family.

I am incredibly proud of the work 343 Industries has done with Halo Infinite, the Master Chief Collection, the Halo TV series and more. It has been an honor for me to serve alongside the team for the past 15 years and be a part of the universe I love.
Bonnie Ross ran the franchise for 15 years and spent 27 years at Microsoft. Phil Spencer thanks woman for her contribution to the development of the Xbox and Halo universes.
Bonnie Ross’s duties were divided among three people. Pierre Hintze was appointed as the new head studio. Bryan Koski will lead the Halo franchise, while Elizabeth Van Wyck will handle the business.

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Source: VG Times